In 2005, Jordana Spiro charmed movie critics and audiences as the ditzy “Sherri” in “Must Love Dogs.” In 2006, Spiro was cast as the lead in the cable comedy series “My Boys,” a critical and cult hit that ran for four seasons.

More recently, Spiro has split her time between roles on the small and big screens, while completing the M.F.A. Program in filmmaking at Columbia University, as well as producing and directing several shorts.

Following her featured role on “Harry’s Law” in 2011, Spiro was cast in a multi-episode arc on “Dexter,” as a follower of the killers played by Colin Hanks and Edward James Olmos. Additional credits include Joel Schumacher’s drama “Trespass,” opposite Nicolas Cage and Nicole Kidman; “The Goods: Live Hard, Sell Hard,” opposite Jeremy Piven, Ed Helms and Rob Riggle; “The Year of Getting to Know Us,” opposite Jimmy Fallon; as well as “Alone with Her”; “Partners”; and “Living & Dying.”

Born and raised in Manhattan, Spiro studied at the Circle in the Square Theatre School and attended the Royal Academy of Dramatic Arts in London.

Spiro currently splits her time between Chicago and New York.